To address the rapidly declining birth rates in 2050, a fanatical evangelical movement seized control of the US government and established a totalitarian theocracy: the Republic of Gilead.
Under Gilead, women have no autonomy and are categorised by function. Wives, the highest-ranking women, gain status from Commanders (Gilead's highest-ranking men). Wives have influence only within their households (as "ladies of the house") and are subject to all prohibitions placed upon women (e.g. no literacy, a legal requirement to comply with their husband's wishes, and arranged betrothals). Other categories of women include Marthas (who are domestic labourers), Handmaids (who serve as reproductive vessels to Commander households), Aunts (who oversee indoctrination and the discipline of women), and Econowives (who shoulder all burdens within lower-class households).
The Underground Femaleroad is a resistance network operated by women throughout Gilead, with notable success in smuggling members out of the country and inflicting damage on the regime through clandestine operations.